Mirtazapine has a therapeutic potency in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mice model of Parkinson’s disease

BACKGROUND: Mirtazapine, a noradrenergic and specific serotonergic antidepressant (NaSSA), shows multiple pharmacological actions such as inhibiting presynaptic α(2) noradrenaline receptor (NAR) and selectively activating 5-hydroxytriptamine (5-HT) 1A receptor (5-HT(1A)R). Mirtazapine was also repor...

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Autori principali: Kadoguchi, Naoto, Okabe, Shinji, Yamamura, Yukio, Shono, Misaki, Fukano, Tatsuya, Tanabe, Akie, Yokoyama, Hironori, Kasahara, Jiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076436/
https://ncbi.nlm.nih.gov/pubmed/24965042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-79
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