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Human Fetal Membranes Generate Distinct Cytokine Profiles in Response to Bacterial Toll-Like Receptor and Nod-Like Receptor Agonists

Bacterial infection-associated inflammation is thought to be a major cause of preterm premature rupture of membranes. Proinflammatory cytokines, such as interleukin 1B (IL1B), can weaken fetal membranes (FM) by upregulating matrix metalloproteinases and inducing apoptosis. The mechanism by which inf...

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Detalhes bibliográficos
Main Authors: Hoang, Mai, Potter, Julie A., Gysler, Stefan M., Han, Christina S., Guller, Seth, Norwitz, Errol R., Abrahams, Vikki M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076407/
https://ncbi.nlm.nih.gov/pubmed/24429216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.113.115428
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