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A novel posttranscriptional mechanism for dietary cholesterol-mediated suppression of liver LDL receptor expression

It is well-established that over-accumulation of dietary cholesterol in the liver inhibits sterol-regulatory element binding protein (SREBP)-mediated LDL receptor (LDLR) gene transcription leading to a reduced hepatic LDLR mRNA level in hypercholesterolemic animals. However, it is unknown whether el...

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書誌詳細
主要な著者: Singh, Amar Bahadur, Kan, Chin Fung Kelvin, Shende, Vikram, Dong, Bin, Liu, Jingwen
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076078/
https://ncbi.nlm.nih.gov/pubmed/24792925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049429
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