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A novel posttranscriptional mechanism for dietary cholesterol-mediated suppression of liver LDL receptor expression
It is well-established that over-accumulation of dietary cholesterol in the liver inhibits sterol-regulatory element binding protein (SREBP)-mediated LDL receptor (LDLR) gene transcription leading to a reduced hepatic LDLR mRNA level in hypercholesterolemic animals. However, it is unknown whether el...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076078/ https://ncbi.nlm.nih.gov/pubmed/24792925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049429 |
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