Transplanted Terminally Differentiated Induced Pluripotent Stem Cells Are Accepted By Immune Mechanisms Similar To Self-Tolerance

The exact nature of the immune response elicited by autologous induced pluripotent stem cell (iPSC) progeny is still not well understood. Here we show in murine models that autologous iPSC-derived endothelial cells (iECs) elicit an immune response that resembles the one against a comparable somatic...

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Detalhes bibliográficos
Main Authors: de Almeida, Patricia E., Meyer, Everett H., Kooreman, Nigel G., Diecke, Sebastian, Dey, Devaveena, Sanchez-Freire, Veronica, Hu, Shijun, Ebert, Antje, Odegaard, Justin, Mordwinkin, Nick, Brouwer, Thomas P., Lo, David, Montoro, Daniel, Longaker, Michael T., Negrin, Robert S., Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075468/
https://ncbi.nlm.nih.gov/pubmed/24875164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4903
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