Costimulation-Adhesion Blockade is Superior to Cyclosporine A and Prednisone Immunosuppressive Therapy for Preventing Rejection of Differentiated Human Embryonic Stem Cells Following Transplantation

RATIONALE: Human embryonic stem cell (hESC) derivatives are attractive candidates for therapeutic use. The engraftment and survival of hESC derivatives as xenografts or allografts require effective immunosuppression to prevent immune cell infiltration and graft destruction. OBJECTIVE: To test the hy...

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Detalhes bibliográficos
Main Authors: Huber, Bruno C., Ransohoff, Julia D., Ransohoff, Katherine J., Riegler, Johannes, Ebert, Antje, Kodo, Kazuki, Gong, Yongquan, Sanchez-Freire, Veronica, Dey, Devaveena, Kooreman, Nigel G., Diecke, Sebastian, Zhang, Wendy Y., Odegaard, Justin, Hu, Shijun, Gold, Joseph D., Robbins, Robert C., Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938393/
https://ncbi.nlm.nih.gov/pubmed/24038578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1501
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