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The epigenome of synovial fibroblasts: an underestimated therapeutic target in rheumatoid arthritis
Perturbed epigenetic landscape and deregulated microRNA networks are central to the permanent activation and aggressiveness of synovial fibroblasts in rheumatoid arthritis. Current anti-cytokine therapies, although effectively halting synovitis, cannot reverse the stably activated destructive phenot...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075141/ https://ncbi.nlm.nih.gov/pubmed/25165988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4596 |
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