Studies on the Q175 Knock-in Model of Huntington’s Disease Using Functional Imaging in Awake Mice: Evidence of Olfactory Dysfunction

Blood oxygen level dependent (BOLD) imaging in awake mice was used to identify differences in brain activity between wild-type, HETzQ175, and HOMzQ175 genotypes in response to the odor of almond. The study was designed to see how alterations in the huntingtin gene in a mouse model of Huntington’s di...

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Bibliografiska uppgifter
Huvudupphovsmän: Ferris, Craig F., Kulkarni, Praveen, Toddes, Steven, Yee, Jason, Kenkel, William, Nedelman, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2014
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074991/
https://ncbi.nlm.nih.gov/pubmed/25071696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2014.00094
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