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Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice

We used behavioral testing and morphological methods to detail the progression of basal ganglia neuron type‐specific pathology and the deficits stemming from them in male heterozygous Q175 mice, compared to age‐matched WT males. A rotarod deficit was not present in Q175 mice until 18 months, but inc...

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Bibliografske podrobnosti
izdano v:J Comp Neurol
Main Authors: Deng, Yunping, Wang, Hongbing, Joni, Marion, Sekhri, Radhika, Reiner, Anton
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049038/
https://ncbi.nlm.nih.gov/pubmed/32869871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.25023
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