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Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice

We used behavioral testing and morphological methods to detail the progression of basal ganglia neuron type‐specific pathology and the deficits stemming from them in male heterozygous Q175 mice, compared to age‐matched WT males. A rotarod deficit was not present in Q175 mice until 18 months, but inc...

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Detalhes bibliográficos
Publicado no:J Comp Neurol
Main Authors: Deng, Yunping, Wang, Hongbing, Joni, Marion, Sekhri, Radhika, Reiner, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049038/
https://ncbi.nlm.nih.gov/pubmed/32869871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.25023
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