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Progression of basal ganglia pathology in heterozygous Q175 knock‐in Huntington's disease mice

We used behavioral testing and morphological methods to detail the progression of basal ganglia neuron type‐specific pathology and the deficits stemming from them in male heterozygous Q175 mice, compared to age‐matched WT males. A rotarod deficit was not present in Q175 mice until 18 months, but inc...

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Bibliografiske detaljer
Udgivet i:J Comp Neurol
Main Authors: Deng, Yunping, Wang, Hongbing, Joni, Marion, Sekhri, Radhika, Reiner, Anton
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049038/
https://ncbi.nlm.nih.gov/pubmed/32869871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.25023
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