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HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation
Antiestrogens including tamoxifen and fulvestrant have been evaluated as chemotherapeutics for ovarian cancer, particularly in cases of platinum resistant disease. Human epididymis protein 4 (HE4) is highly overexpressed in women with ovarian cancer and overexpression of HE4 has been found to correl...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074789/ https://ncbi.nlm.nih.gov/pubmed/24975515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05500 |
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