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Mild Renal Dysfunction and Metabolites Tied to Low HDL Cholesterol Are Associated With Monocytosis and Atherosclerosis

BACKGROUND: The number of circulating blood monocytes impacts atherosclerotic lesion size, and in mouse models, elevated levels of high-density lipoprotein cholesterol suppress blood monocyte counts and atherosclerosis. We hypothesized that individuals with mild renal dysfunction at increased cardio...

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Main Authors: Ganda, Anjali, Magnusson, Martin, Yvan-Charvet, Laurent, Hedblad, Bo, Engström, Gunnar, Ai, Ding, Wang, Thomas J., Gerszten, Robert E., Melander, Olle, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074592/
https://ncbi.nlm.nih.gov/pubmed/23378299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.000682
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