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A gene score of nine LDL and HDL regulating genes is associated with fluvastatin-induced cholesterol changes in women

While conventional pharmacogenetic studies have considered single gene effects, we tested if a genetic score of nine LDL- and HDL-associated single nucleotide polymorphisms, previously shown to predict cardiovascular disease, is related to fluvastatin-induced lipid change. In patients with asymptoma...

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Detalhes bibliográficos
Main Authors: Hamrefors, Viktor, Orho-Melander, Marju, Krauss, Ronald M., Hedblad, Bo, Almgren, Peter, Berglund, Göran, Melander, Olle
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817592/
https://ncbi.nlm.nih.gov/pubmed/19773416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P001792
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