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p53 and Mitochondrial Function in Neurons

The p53 tumor suppressor plays a central role in dictating cell survival and death as a cellular sensor for a myriad of stresses including DNA damage, oxidative and nutritional stress, ischemia and disruption of nucleolar function. Activation of p53-dependent apoptosis leads to mitochondrial apoptot...

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Bibliografiske detaljer
Main Authors: Wang, David B., Kinoshita, Chizuru, Kinoshita, Yoshito, Morrison, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074561/
https://ncbi.nlm.nih.gov/pubmed/24412988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.12.015
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