Declines in Drp1 and Parkin Expression Underlie DNA Damage-Induced Changes in Mitochondrial Length and Neuronal Death

Maintaining proper mitochondrial length is essential for normal mitochondrial function in neurons. Mitochondrial fragmentation has been associated with neuronal cell death caused by a variety of experimental toxic stressors. Despite the fact that oxidative stress is a hallmark of neurodegenerative c...

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Hauptverfasser: Wang, David B., Garden, Gwenn A., Kinoshita, Chizuru, Wyles, Cody, Babazadeh, Nasim, Sopher, Bryce, Kinoshita, Yoshito, Morrison, Richard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711762/
https://ncbi.nlm.nih.gov/pubmed/23345212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3365-12.2013
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