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p53 and Mitochondrial Function in Neurons
The p53 tumor suppressor plays a central role in dictating cell survival and death as a cellular sensor for a myriad of stresses including DNA damage, oxidative and nutritional stress, ischemia and disruption of nucleolar function. Activation of p53-dependent apoptosis leads to mitochondrial apoptot...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074561/ https://ncbi.nlm.nih.gov/pubmed/24412988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.12.015 |
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