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Beyond Standard Molecular Dynamics: Investigating the Molecular Mechanisms of G Protein-Coupled Receptors with Enhanced Molecular Dynamics Methods

The majority of biological processes mediated by G Protein-Coupled Receptors (GPCRs) take place on timescales that are not conveniently accessible to standard molecular dynamics (MD) approaches, notwithstanding the current availability of specialized parallel computer architectures, and efficient si...

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Detalhes bibliográficos
Main Authors: Johnston, Jennifer M., Filizola, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074508/
https://ncbi.nlm.nih.gov/pubmed/24158803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-7423-0_6
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