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Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

Carrier-facilitated pyruvate transport across the inner mitochondrial membrane plays an essential role in anabolic and catabolic intermediary metabolism. The mitochondrial pyruvate carrier 2 (Mpc2) is believed to be a component of the complex that facilitates mitochondrial pyruvate import. Complete...

詳細記述

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書誌詳細
主要な著者: Vigueira, Patrick A., McCommis, Kyle S., Schweitzer, George G., Remedi, Maria S., Chambers, Kari T., Fu, Xiaorong, McDonald, William G., Cole, Serena L., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074444/
https://ncbi.nlm.nih.gov/pubmed/24910426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.05.017
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