The genetic basis for inactivation of Wnt pathway in human osteosarcoma

BACKGROUND: Osteosarcoma is a highly genetically unstable tumor with poor prognosis. We performed microarray-based comparative genomic hybridization (aCGH), transcriptome sequencing (RNA-seq), and pathway analysis to gain a systemic view of the pathway alterations of osteosarcoma. METHODS: aCGH expe...

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Autores principales: Du, Xiaoling, Yang, Jilong, Yang, Da, Tian, Wei, Zhu, Ze
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074405/
https://ncbi.nlm.nih.gov/pubmed/24942472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-450
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