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Genomic amplification and high expression of EGFR are key targetable oncogenic events in malignant peripheral nerve sheath tumor

BACKGROUND: The dismal outcome of malignant peripheral nerve sheath tumor (MPNST) highlights the necessity of finding new therapeutic methods to benefit patients with this aggressive sarcoma. Our purpose was to investigate epidermal growth factor receptor (EGFR) as a potential therapeutic target in...

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Bibliografische gegevens
Hoofdauteurs: Du, Xiaoling, Yang, Jilong, Ylipää, Antti, Zhu, Ze
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878771/
https://ncbi.nlm.nih.gov/pubmed/24341609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-93
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