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Polyphyllin I suppresses human osteosarcoma growth by inactivation of Wnt/β-catenin pathway in vitro and in vivo

Osteosarcoma is the most common primary bone cancer in children and adolescents. In spite of aggressive treatment, osteosarcoma has a high mortality rate with minimal improvements in survival over past few decades. Polyphyllin I (PPI), a component in the traditional Chinese medicinal herb Paris poly...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Chang, Junli, Li, Yimian, Wang, Xianyang, Hu, Shaopu, Wang, Hongshen, Shi, Qi, Wang, Yongjun, Yang, Yanping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548759/
https://ncbi.nlm.nih.gov/pubmed/28790389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07194-9
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