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RAG1 reversion mosaicism in a patient with Omenn syndrome

PURPOSE: To identify mechanisms of disease in a child born to consanguineous parents, who presented with Omenn syndrome (OS) and was found to carry a heterozygous RAG1 mutation in peripheral blood DNA. METHODS: Mutation analysis was performed on whole blood and buccal swab DNA. Recombination activit...

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Detalhes bibliográficos
Main Authors: Crestani, Elena, Choo, Sharon, Frugoni, Francesco, Lee, Yu Nee, Richards, Stephanie, Smart, Joanne, Notarangelo, Luigi D
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074377/
https://ncbi.nlm.nih.gov/pubmed/24817258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-014-0051-2
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