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Chlamydial infection of monocytes stimulates IL-1β secretion through activation of the NLRP3 inflammasome

Chlamydia trachomatis infections represent the leading cause of bacterial sexually-transmitted disease in the United States and can cause serious tissue damage leading to infertility and ectopic pregnancies in women. Inflammation and hence the innate immune response to chlamydial infection contribut...

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Bibliographic Details
Main Authors: Abdul-Sater, Ali A., Saïd-Sadier, Najwane, Padilla, Eduardo V., Ojcius, David M.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074088/
https://ncbi.nlm.nih.gov/pubmed/20434582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2010.04.008
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