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Activation of the NLRP3 inflammasome by vault nanoparticles expressing a chlamydial epitope

The full potential of vaccines relies on development of effective delivery systems and adjuvants and is critical for development of successful vaccine candidates. We have shown that recombinant vaults engineered to encapsulate microbial epitopes are highly stable structures and are an ideal vaccine...

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Publicado en:Vaccine
Autores principales: Zhu, Ye, Jiang, Janina, Said-Sadier, Najwane, Boxx, Gale, Champion, Cheryl, Tetlow, Ashley, Kickhoefer, Valerie A., Rome, Leonard H., Ojcius, David M., Kelly, Kathleen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272900/
https://ncbi.nlm.nih.gov/pubmed/25448112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.11.028
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