Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

Invasive aspergillosis (IA) is a life-threatening disease that occurs in immunodepressed patients when infected with Aspergillus fumigatus. This fungus is the second most-common causative agent of fungal disease after Candida albicans. Nevertheless, much remains to be learned about the mechanisms by...

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Bibliographic Details
Main Authors: Saïd-Sadier, Najwane, Padilla, Eduardo, Langsley, Gordon, Ojcius, David M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848854/
https://ncbi.nlm.nih.gov/pubmed/20368800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010008
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