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PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells
Elevated levels of intracellular Ca(2+) ([Ca(2+)](i)) inhibit Na(+)/H(+) exchanger 3 (NHE3) activity in the intact intestine. We previously demonstrated that PLC-γ directly binds NHE3, an interaction that is necessary for [Ca(2+)](i) inhibition of NHE3 activity, and that PLC-γ Src homology 2 (SH2) d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073947/ https://ncbi.nlm.nih.gov/pubmed/23703528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00277.2012 |
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