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Carbachol regulation of rabbit ileal brush border Na(+)–H(+) exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src dependent

The epithelial brush border membrane (BBM) Na(+)–H(+) exchanger 3 (NHE3) is the major transport protein responsible for ileal electroneutral Na(+) absorption. We have previously shown that ileal BBM NHE3 activity is rapidly inhibited by carbachol, an agonist that mimics cholinergic activation in dig...

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Detalhes bibliográficos
Main Authors: Li, Xuhang, Zhang, Huiping, Cheong, Alice, Yueping Chen, Sharon Leu, Elowsky, Christian G, Donowitz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664999/
https://ncbi.nlm.nih.gov/pubmed/14978207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.060921
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