Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro

Polarized and pseudostratified primary airway epithelia present barriers that significantly reduce their transfection efficiency and the efficacy of RNA interference oligonucleotides. This creates an impediment in studies of the airway epithelium, diminishing the utility of loss-of-function as a res...

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Detalles Bibliográficos
Main Authors: Ramachandran, Shyam, Krishnamurthy, Sateesh, Jacobi, Ashley M., Wohlford-Lenane, Christine, Behlke, Mark A., Davidson, Beverly L., McCray, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2013
Assuntos:
Innovative Methodology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073929/
https://ncbi.nlm.nih.gov/pubmed/23624792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00426.2012
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