Influence of Cell Polarity on Retrovirus-Mediated Gene Transfer to Differentiated Human Airway Epithelia

Gene transfer with recombinant murine leukemia viruses (MuLV) provides the potential to permanently correct inherited lung diseases, such as cystic fibrosis (CF). Several problems prevent the application of MuLV-based recombinant retroviruses to lung gene therapy: (i) the lack of cell proliferation...

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Detalhes bibliográficos
Main Authors: Wang, Guoshun, Davidson, Beverly L., Melchert, Paul, Slepushkin, Vladimir A., van Es, Helmuth H. G., Bodner, Mordechai, Jolly, Doug J., McCray, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110493/
https://ncbi.nlm.nih.gov/pubmed/9811717
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