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Influence of Cell Polarity on Retrovirus-Mediated Gene Transfer to Differentiated Human Airway Epithelia

Gene transfer with recombinant murine leukemia viruses (MuLV) provides the potential to permanently correct inherited lung diseases, such as cystic fibrosis (CF). Several problems prevent the application of MuLV-based recombinant retroviruses to lung gene therapy: (i) the lack of cell proliferation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Guoshun, Davidson, Beverly L., Melchert, Paul, Slepushkin, Vladimir A., van Es, Helmuth H. G., Bodner, Mordechai, Jolly, Doug J., McCray, Paul B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110493/
https://ncbi.nlm.nih.gov/pubmed/9811717
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