Moderate tidal volumes and oxygen exposure during initiation of ventilation in preterm fetal sheep

BACKGROUND: Preterm infants often receive mechanical ventilation and oxygen at birth. Exposure to large tidal volumes (V(T)) at birth causes lung inflammation and oxygen may amplify the injury. We hypothesized that normal V(T) ventilation at birth causes lung injury that is exacerbated by 95% oxygen...

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Bibliographic Details
Main Authors: Hillman, Noah H., Moss, Timothy J, Nitsos, Ilias, Jobe, Alan H.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073615/
https://ncbi.nlm.nih.gov/pubmed/23037872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.135
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