Positive end-expiratory pressure and surfactant decrease lung injury during initiation of ventilation in fetal sheep

The initiation of ventilation in preterm, surfactant-deficient sheep without positive end-expiratory pressure (PEEP) causes airway injury and lung inflammation. We hypothesized that PEEP and surfactant treatment would decrease the lung injury from initiation of ventilation with high tidal volumes. F...

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Main Authors: Hillman, Noah H., Nitsos, Ilias, Berry, Clare, Jane Pillow, J., Kallapur, Suhas G., Jobe, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290453/
https://ncbi.nlm.nih.gov/pubmed/21856815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00157.2011
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