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Moderate tidal volumes and oxygen exposure during initiation of ventilation in preterm fetal sheep

BACKGROUND: Preterm infants often receive mechanical ventilation and oxygen at birth. Exposure to large tidal volumes (V(T)) at birth causes lung inflammation and oxygen may amplify the injury. We hypothesized that normal V(T) ventilation at birth causes lung injury that is exacerbated by 95% oxygen...

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Detalhes bibliográficos
Main Authors: Hillman, Noah H., Moss, Timothy J, Nitsos, Ilias, Jobe, Alan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073615/
https://ncbi.nlm.nih.gov/pubmed/23037872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2012.135
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