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Dasatinib inhibits both osteoclast activation and prostate cancer PC-3 cell-induced osteoclast formation

PURPOSE: Therapies to target prostate cancer bone metastases have only limited effects. New treatments are focused on the interaction between cancer cells, bone marrow cells and the bone matrix. Osteoclasts play an important role in the development of bone tumors caused by prostate cancer. Since Src...

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Bibliografiska uppgifter
Huvudupphovsmän: Araujo, John C., Poblenz, Ann, Corn, Paul G., Parikh, Nila U., Starbuck, Michael W., Thompson, Jerry T., Lee, Francis, Logothetis, Christopher J., Darnay, Bryant G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073296/
https://ncbi.nlm.nih.gov/pubmed/19855158
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