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Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors
SRC is a tyrosine kinase that plays a role in oncogenic, invasive and bone-metastatic processes. It has therefore been prioritized as a candidate therapeutic target in patients with solid tumors. Several SRC inhibitors are now in development, of which dasatinib has been most explored. Preclinical st...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3940067/ https://ncbi.nlm.nih.gov/pubmed/20226597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2010.02.015 |
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