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Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish

The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expression of hundreds of targets. UPR activation can resul...

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Detalhes bibliográficos
Main Authors: Vacaru, Ana M., Di Narzo, Antonio Fabio, Howarth, Deanna L., Tsedensodnom, Orkhontuya, Imrie, Dru, Cinaroglu, Ayca, Amin, Salma, Hao, Ke, Sadler, Kirsten C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073272/
https://ncbi.nlm.nih.gov/pubmed/24973751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014472
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