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Atf6 plays protective and pathologic roles in fatty liver disease due to endoplasmic reticulum stress

Many etiologies of fatty liver disease (FLD) are associated with hyper-activation of one of the three pathways that comprise the unfolded protein response (UPR), a harbinger of endoplasmic reticulum (ER) stress. The UPR is mediated by pathways initiated by PERK, IRE1a/XBP1and ATF6, and each of these...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cinaroglu, Ayca, Gao, Chuan, Imrie, Dru, Sadler, Kirsten C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145024/
https://ncbi.nlm.nih.gov/pubmed/21538441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24396
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