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Atf6 plays protective and pathologic roles in fatty liver disease due to endoplasmic reticulum stress
Many etiologies of fatty liver disease (FLD) are associated with hyper-activation of one of the three pathways that comprise the unfolded protein response (UPR), a harbinger of endoplasmic reticulum (ER) stress. The UPR is mediated by pathways initiated by PERK, IRE1a/XBP1and ATF6, and each of these...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145024/ https://ncbi.nlm.nih.gov/pubmed/21538441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24396 |
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