Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish

The unfolded protein response (UPR) is a complex network of sensors and target genes that ensure efficient folding of secretory proteins in the endoplasmic reticulum (ER). UPR activation is mediated by three main sensors, which regulate the expression of hundreds of targets. UPR activation can resul...

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Main Authors: Vacaru, Ana M., Di Narzo, Antonio Fabio, Howarth, Deanna L., Tsedensodnom, Orkhontuya, Imrie, Dru, Cinaroglu, Ayca, Amin, Salma, Hao, Ke, Sadler, Kirsten C.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073272/
https://ncbi.nlm.nih.gov/pubmed/24973751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014472
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