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An ion-current-based, comprehensive and reproducible proteomic strategy for comparative characterization of the cellular responses to novel anti-cancer agents in a prostate cell model

Proteome-level investigation of the molecular targets in anticancer action of promising pharmaceutical candidates is highly desirable but remains challenging due to the insufficient proteome coverage, limited capacity for biological replicates, and largely unregulated false positive biomarker discov...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Tu, Chengjian, Li, Jun, Bu, Yahao, Hangauer, David, Qu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073256/
https://ncbi.nlm.nih.gov/pubmed/22982362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2012.08.020
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