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Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis
BACKGROUND: RNA interference (RNAi) is an effective and important tool used to study gene function. For large-scale screens, RNAi is used to systematically down-regulate genes of interest and analyze their roles in a biological process. However, RNAi is associated with off-target effects (OTEs), inc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4073188/ https://ncbi.nlm.nih.gov/pubmed/24934636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-192 |
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