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RNAi screening comes of age: improved techniques and complementary approaches
Gene silencing through sequence-specific targeting of mRNAs by RNAi has enabled genome-wide functional screens in cultured cells and in vivo in model organisms. These screens have resulted in the identification of new cellular pathways and potential drug targets. Considerable progress has been made...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4204798/ https://ncbi.nlm.nih.gov/pubmed/25145850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3860 |
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