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Localized In Vivo Activation of a Photoactivatable Doxorubicin Prodrug in Deep Tumor Tissue
Sparing sensitive healthy tissue from chemotherapy exposure is a critical challenge in the treatment of cancer. The work described here demonstrates the localized in vivo photo-activation of a new chemotherapy prodrug of doxorubicin (DOX). The DOX prodrug (DOX-PCB) was 200 times less toxic to cells,...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4072807/ https://ncbi.nlm.nih.gov/pubmed/23311544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12045 |
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