Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis

Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishmania donovani. Previously we found that parasite-induced arg1 expression in macrophages was dependen...

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Hlavní autoři: Osorio, E. Yaneth, Travi, Bruno L., da Cruz, Alda M., Saldarriaga, Omar A., Medina, Audrie A., Melby, Peter C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072777/
https://ncbi.nlm.nih.gov/pubmed/24967908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004165
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