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VPA Alleviates Neurological Deficits and Restores Gene Expression in a Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a devastating neurodevelopmental disorder that occurs once in every 10,000–15,000 live female births. Despite intensive research, no effective cure is yet available. Valproic acid (VPA) has been used widely to treat mood disorder, epilepsy, and a growing number of other disord...

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Autores principales: Guo, Weixiang, Tsujimura, Keita, Otsuka I., Maky, Irie, Koichiro, Igarashi, Katsuhide, Nakashima, Kinichi, Zhao, Xinyu
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072629/
https://ncbi.nlm.nih.gov/pubmed/24968028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100215
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