VPA Alleviates Neurological Deficits and Restores Gene Expression in a Mouse Model of Rett Syndrome

Rett syndrome (RTT) is a devastating neurodevelopmental disorder that occurs once in every 10,000–15,000 live female births. Despite intensive research, no effective cure is yet available. Valproic acid (VPA) has been used widely to treat mood disorder, epilepsy, and a growing number of other disord...

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Detalhes bibliográficos
Main Authors: Guo, Weixiang, Tsujimura, Keita, Otsuka I., Maky, Irie, Koichiro, Igarashi, Katsuhide, Nakashima, Kinichi, Zhao, Xinyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072629/
https://ncbi.nlm.nih.gov/pubmed/24968028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100215
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