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The lysosomal cathepsin protease CPL-1 plays a leading role in phagosomal degradation of apoptotic cells in Caenorhabditis elegans

During programmed cell death, the clearance of apoptotic cells is achieved by their phagocytosis and delivery to lysosomes for destruction in engulfing cells. However, the role of lysosomal proteases in cell corpse destruction is not understood. Here we report the identification of the lysosomal cat...

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Hlavní autoři: Xu, Meng, Liu, Yubing, Zhao, Liyuan, Gan, Qiwen, Wang, Xiaochen, Yang, Chonglin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072580/
https://ncbi.nlm.nih.gov/pubmed/24829385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0015
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