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Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation

Phagocytosis of apoptotic cells requires recognition of cell corpses followed by internalization and enclosure within plasma membrane-derived phagosomes. Phagosomes undergo maturation to generate phagolysosomes in which cell corpses are degraded; however, regulation of the maturation process is poor...

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Detalhes bibliográficos
Main Authors: Guo, Pengfei, Hu, Tianjing, Zhang, Juan, Jiang, Shanya, Wang, Xiaochen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964220/
https://ncbi.nlm.nih.gov/pubmed/20921409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008946107
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