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Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans

Efficient clearance of apoptotic cells by phagocytes is important for development, tissue homeostasis, and the prevention of autoimmune responses. Phagosomes containing apoptotic cells undergo acidification and mature from Rab5-positive early to Rab7-positive late stages. Phagosomes finally fuse wit...

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Detalhes bibliográficos
Main Authors: Sasaki, Ayaka, Nakae, Isei, Nagasawa, Maya, Hashimoto, Keisuke, Abe, Fumiko, Saito, Kota, Fukuyama, Masamitsu, Gengyo-Ando, Keiko, Mitani, Shohei, Katada, Toshiaki, Kontani, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655818/
https://ncbi.nlm.nih.gov/pubmed/23485564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-08-0628
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