Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans

Efficient clearance of apoptotic cells by phagocytes is important for development, tissue homeostasis, and the prevention of autoimmune responses. Phagosomes containing apoptotic cells undergo acidification and mature from Rab5-positive early to Rab7-positive late stages. Phagosomes finally fuse wit...

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Bibliographic Details
Main Authors: Sasaki, Ayaka, Nakae, Isei, Nagasawa, Maya, Hashimoto, Keisuke, Abe, Fumiko, Saito, Kota, Fukuyama, Masamitsu, Gengyo-Ando, Keiko, Mitani, Shohei, Katada, Toshiaki, Kontani, Kenji
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655818/
https://ncbi.nlm.nih.gov/pubmed/23485564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-08-0628
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