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A human-specific allelic group of the MHC DRB1 gene in primates

BACKGROUND: Diversity among human leukocyte antigen (HLA) molecules has been maintained by host-pathogen coevolution over a long period of time. Reflecting this diversity, the HLA loci are the most polymorphic in the human genome. One characteristic of HLA diversity is long-term persistence of allel...

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Autors principals: Yasukochi, Yoshiki, Satta, Yoko
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072476/
https://ncbi.nlm.nih.gov/pubmed/24928070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1880-6805-33-14
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