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Nonsynonymous Substitution Rate Heterogeneity in the Peptide-Binding Region Among Different HLA-DRB1 Lineages in Humans
An extraordinary diversity of amino acid sequences in the peptide-binding region (PBR) of human leukocyte antigen [HLA; human major histocompatibility complex (MHC)] molecules has been maintained by balancing selection. The process of accumulation of amino acid diversity in the PBR for six HLA genes...
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| Publicado no: | G3 (Bethesda) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4455771/ https://ncbi.nlm.nih.gov/pubmed/24793785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.011726 |
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